this is about how a protein binding that regulates the activity of elf4E, can regulate the activity of fat burn. (This is in fruit fly model, not in a human model). And it's a hot topic, since it made it to Cold Spring Harbor Journal.

http://www.biolchem.ucla.edu/hh_jclub/paper1.pdf
http://www.biolchem.ucla.edu/hh_jclub/paper2.pdf

Let me know what you guys think?!!