View Full Version : TPR Q: increased level of testosterone in blood decreases the production of FSH?


premed08
05-17-2008, 03:00 PM
I was reading TPR biology and came across this question on pg.326. I dont understand why this would happen. I expected the opposite since testosterone stimulates spermatogenesis and FSH stimulates sertolli cells aid spermatogensis. So wouldn't it be high lebels of testosterone would lead higher levels of FSh in the blood?

Anybody?

BloodySurgeon
05-17-2008, 03:09 PM
Hypothalamus --> GnrH ---> Anterior Pituitary ----> LH --> Leydig cells ---> testosterone.

To counter the effects of too much testosterone, testosterone does a negative feedback on the hypothalmus to inhibit GnrH which inhibits both LH and FSH.