View Full Version : Destroyer Organic # 184


dsjar
07-16-2008, 09:54 AM
Hey guys just wondering if someone can help me out on this problem
I understand what happens and the mechanism but i got choice E. How do you know which alpha proton get removed. I though it would be the left one which give you E, but the answer is B.
Helllp!
Thanks : )

klutzy1987
07-16-2008, 10:56 AM
Unless there i a dialpha proton always remove the least sterically hindered Hydrogen (primary first). If you have a dialpha then that comes first.

Orgodox
07-16-2008, 11:33 AM
Yea someone asked about this last week but like klutzy said you gotta remove from the side thats less hindered