So i know that high progesterone levels will keep ovualtion from occuring, but what kind of effect does it have on FSH? Does it inhibit FSH to prevent ovulation? I have it written in my notes that it inhibits it but then i have it in here that FSH and LH levels increase when hcG takes over, which doesn't make sense.

So i know that high progesterone levels will keep ovualtion from occuring, but what kind of effect does it have on FSH? Does it inhibit FSH to prevent ovulation? I have it written in my notes that it inhibits it but then i have it in here that FSH and LH levels increase when hcG takes over, which doesn't make sense.

Remember that after ovulation, the follicle develops into the corpus luteum which will produce estrogen and progesterone. Both estrogen and progesterone acts on the hypothalamus and anterior pituitary to inhibit secretion of GnRH, LH and FSH. (negative feedback)

HcG (Human chorionic gonadotropin) does not increase the levels of FSH and LH. If fertilization occurs, the placenta will form which releases HcG. HcG acts on the corpus luteum to continue producing estrogen and progesterone. FYI: pregnancy tests detect levels of HcG because the placenta secretes this hormone and only when youre pregnant do you produce a placenta.

This is all done because, once you have fertilization, you would not want to produce FSH and LH. FSH (follicle stimulating hormone) --> Fertilization happened! Why develop more follicles?

Hope thats not all too confusing.

So i know that high progesterone levels will keep ovualtion from occuring, but what kind of effect does it have on FSH? Does it inhibit FSH to prevent ovulation? I have it written in my notes that it inhibits it but then i have it in here that FSH and LH levels increase when hcG takes over, which doesn't make sense.


I always thought progesterone was synthesized by the corpus luteum as a result of ovulation.

LH is what causes ovulation and from there it becomes the corpus luteum which synthesizes progesterone that prepares for implantation. Hope that helps, PM me if you need any more info.

Remember that after ovulation, the follicle develops into the corpus luteum which will produce estrogen and progesterone. Both estrogen and progesterone acts on the hypothalamus and anterior pituitary to inhibit secretion of GnRH, LH and FSH. (negative feedback)

HcG (Human chorionic gonadotropin) does not increase the levels of FSH and LH. If fertilization occurs, the placenta will form which releases HcG. HcG acts on the corpus luteum to continue producing estrogen and progesterone. FYI: pregnancy tests detect levels of HcG because the placenta secretes this hormone and only when youre pregnant do you produce a placenta.

This is all done because, once you have fertilization, you would not want to produce FSH and LH. FSH (follicle stimulating hormone) --> Fertilization happened! Why develop more follicles?

Hope thats not all too confusing.
:thumbup: well put

also keep in mind that progesterones job is to maintain the endometrium (to get ready for implantation). so basically u need hormones to help out with the endometrium and you need less hormones contributing to making more eggs

alright well i guess that makes sense. but one more question :). During ovulation, do both estrogen and LH increase and estradiol levels decrease?

haha are the guys in this forum teacing the girls? that's funy, because i dont get this stuff either and probably should!:laugh:

QUESTION: what exactly is the corpus luteum (the ovum???)

(too much the office)

During ovulation, LH surge is what causes the follicle to rupture and release the primary oocyte. At the time of ovulation, estrogen levels are high but it is the the LH that actually leads to ovulation. I read that the LH surge causes release of enzymes that breaks down the follicle membrane.

As for estradiol decrease? Not too sure... isn't estradiol just a form of estrogen?

haha are the guys in this forum teacing the girls? that's funy, because i dont get this stuff either and probably should!:laugh:

QUESTION: what exactly is the corpus luteum (the ovum???)

(too much the office)

the corpus luteum is the remains of the follicle cell after ovulation

the ovum is in the follicle though right? where else would it come from??

What gets released from the follicle is the primary oocyte. The entire follicle itself is a collection of cells. From inside out...

oocyte>>zona pellucida>>granulosa cells>>theca cells.

yeah estradiol is a form of estrogen, it's the main source of it. it's from the graafin follicle encasing an egg. schaum's says that estradiol shows a sharp drop during ovulation when the LH hits a high peak. but was just wondering. i guess estradiol decreases b/c a lot of estrogen is being made? ah, i dunno. but you should know that estradiol is involved in teh Luteal phase though.

awesome explanations guys! :)

yeah estradiol is a form of estrogen, it's the main source of it. it's from the graafin follicle encasing an egg. schaum's says that estradiol shows a sharp drop during ovulation when the LH hits a high peak. but was just wondering. i guess estradiol decreases b/c a lot of estrogen is being made? ah, i dunno. but you should know that estradiol is involved in teh Luteal phase though.

awesome explanations guys! :)

ah, ok i think i get it. To make it simple I would consider the two the same thing. The sharp drop in estradiol (estrogen) after ovulation is due to the rupture of the follicle cells and no more production of estrogen since it was the follicle cells producing the estrogen in the first place. But once the follicular cells become the corpus luteum, you will begin to see a slow rise the estrogen/progesterone level.

yup, that makes sense!

I am

I just jealous of girls who know that it is so easy to study ...no offense just it's hard for us men to get it easily
GL