Unless there's a ring on a finger -- and by no means am I suggesting a proposal (can you say desperation?) -- each party needs to decide independently from one another what's going to be in their best interest. If that means the relationship ends then so be it. Though DMU is indeed a great school, based upon what she has said with respect to her career aspirations, it appears MD is going to be best for her.
I'm assuming this isn't exactly what you were looking for, but tough love it is. Unfortunately, that's the reality of it.