About the ads

Go Back   Student Doctor Network Forums > Dental Forums [ DDS / DMD ] > DAT Discussions
Reload this Page DAT Destroyer OC #156(Claisen)
Register FAQ SDN Live Mark Forums Read

DAT Discussions Discuss study tips and resources to excel on the Dental Admissions Test. RSS: Feed Icon


Reply
 
Thread Tools Display Modes
Old 05-03-2012, 08:16 PM   #1
Member
 
Status: Pre-Dental
Join Date: Feb 2012
Posts: 44

Default DAT Destroyer OC #156(Claisen)

SDN Members don't see this ad. (About Ads)
So I understand the initial Claisen. But the second step is the addition of an acid. Why wouldn't the resulting ester hydrolyze, giving you a carboxylic acid beta to a ketone, which would decarboxylate?
jwest88 is offline   Reply With Quote
Old 05-04-2012, 07:03 AM   #2
Senior Member
 
Join Date: May 2007
Posts: 873
SDN 5+ Year Member
Default
Because you first hydrolyze the ester with base, the protonate acetate anion with acid. Once you generate a Beta keto acid, it can be decarboxylated by adding heat. Only bet ketoacids ( acids on the beta carbon) can be decarboxylated with heat. Hope this helps.

Sent from my MB855 using Tapatalk
Dotoday is offline   Reply With Quote
Old 05-04-2012, 08:16 AM   #3
Member
 
Status: Pre-Dental
Join Date: Feb 2012
Posts: 44

Default
O, ok I totally forgot that you have to add heat. Thanks a bunch.
jwest88 is offline   Reply With Quote

Reply

Bookmarks

« Previous Thread | Next Thread »
Thread Tools
Display Modes
Linear Mode Linear Mode

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts
BB code is On
Smilies are On
[IMG] code is On
HTML code is Off
Forum Jump


All times are GMT -7. The time now is 06:35 AM.


Comments are closed.