Fibrin Disc Injections

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http://www.youtube.com/watch?v=EJV4v0S0cSw

Roger Chou, Rick Deyo, and the other meta-analyticians must be reeling at the thought...

I give Dr. Pauza props for not giving up after IDET.

Originally Posted by drusso

Roger Chou, Rick Deyo, and the other meta-analyticians must be reeling at the thought...

I give Dr. Pauza props for not giving up after IDET.

I think they'd chastise him for his enthusiasm in spite of hard data. But otherwise, they would likely see this - if proven effective - a much more cost-effective and less morbid alternative to TDR or fusion.

IS this guy serious? He's basically doing a discogram but w/o a Mask, gown, or a cap??

He claims to 'restore the height' of the disc as well........

What's stopping the goo from leaking out into the epidural space?

Originally Posted by Taus

What's stopping the goo from leaking out into the epidural space?

or the nerve root!

I think when a disc is severely narrowed the person has more facet pain as the joint assumes more of the load. Some people have disc pain without much loss of height. The nucleus has no nerves. I just don't get the rationale for intra-discal anything.

The live fluoro did appear to show the endplates separating (or maybe I was seeing things). If nothing else, seems more logical than ozone or methylene blue intradiscally.

He is charging $5,000 cash plus per case per the video

It would be great to have better solutions that are nonsurgical for discogenic pain. My suspicion is the initial very positive anecdotal evidence will ultimately be refuted by poor outcomes in clinical trials.

We shall see

Can't see the video! But his study is quite old! if I remember correctly, he published it one of ISIS news letter in 2007. As per this study, he put 1 ml fibrin sealant after IDET or Nucleoplasty.
Interseted in others view of various Intradiscal therapies, please contribute!

I'm surprised he doesn't mix some Omnipaque into his concoction...unless there is some issue with them mixing...I would be way too paranoid about epidural spread of "stuff that congeals" ala PMMA for vertebral augmentation.

I think it makes a lot of sense. Big deal if it spreads into the epidural space, there is generally some room for fibrin mass there, and fibrin has been used for PDPH patches directly in the epidural space so should be safe. Hope this turns out.

Originally Posted by pmrmd

I think when a disc is severely narrowed the person has more facet pain as the joint assumes more of the load. Some people have disc pain without much loss of height. The nucleus has no nerves. I just don't get the rationale for intra-discal anything.

agree, in loss of disc height, its physics. the joint is suppose to have some height to have it in proper place, from the disc. its a spacer

Originally Posted by pmrmd

I think when a disc is severely narrowed the person has more facet pain as the joint assumes more of the load. Some people have disc pain without much loss of height. The nucleus has no nerves. I just don't get the rationale for intra-discal anything.

The annulus has a nerve supply: The sinovertebral nerve and GRC.

Yes Well said drusso

it's just PRP with his patented syringe system...cool video after you work around the maze of Obama reelection ads on youtube. Ironic.