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Old 06-01-2011, 05:13 PM   #1
4G MD
 
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Default NMJ AChR upregulation causes


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NMJ AChR upregulation causes
Nicotinic AChR upregulation:
• Spinal cord injury
• Stroke
• Burns
• Prolonged immobility
• Prolonged exposure to neuromuscular blockers
• Multiple sclerosis
• Guillain-Barre syndrome
Nicotinic AChR downregulation
• Myasthenia gravis
• Anticholinesterase poisoning
• Organophosphate poisoning
[Miller Box 29-1]
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