I have a Hospice patient (82 yo female w/ metastatic AdenoCa of the lung) who has developed appendicular and axial rigidity along with hoarshness/hypophonia. She has no prior Hx of PD, and the Sx developed shortly after she was prescribed a fentanyl patch
(100mcg/hr, increased from 50mcg/hr). She has also become stuporous. Her PCP had prescibed Marinol and Ativan, but these were d/c'd.
I know that opiates/opioids have been associated with muscular rigidity, but theliterature is far from clear about this or what should be done about it. Any comments?
(100mcg/hr, increased from 50mcg/hr). She has also become stuporous. Her PCP had prescibed Marinol and Ativan, but these were d/c'd.
I know that opiates/opioids have been associated with muscular rigidity, but theliterature is far from clear about this or what should be done about it. Any comments?