I applied 3 times.
First year I applied to only 4 schools and to be honest, I wasn't very smart with which schools I applied to. I was waitlisted and never got off the waitlist.
Between first and second year, I retook the GRE (my verbal score was horrendous). I improved that score by an ok amount. I also looked for more large animal experience and started to do some volunteer work with horses.
Second year, I applied to 6 schools, got a few interviews, waitlisted at one school, never got off the waitlist.
Between second and third year, I researched the schools more. Focused my application to schools that I was more likely to be accepted to. I also gained a little equine veterinary experience and continued the volunteer work with horses. I had plenty of small animal experience, so that was not a point I needed to address. I did retake the GRE again, and I improved my verbal score by a bit more. I also reworked my Personal Statement and the essays on the supplemental applications. I have an issue with stating why I am a good candidate and not being shy about it, I didn't want to come across as "full of myself" when in reality, I just needed to show that I believe in myself and that I do believe I can succeed.
Third Year: I applied to one international school and 6 US schools. I was on two waitlists in the US. I was accepted internationally.
As how to mentally prepare for it, it kind of became like riding a bike to me by the third year....
After falling, you have to just get back on and keep pedaling.