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- Jul 23, 2011
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Does anyone know why 1-Fluoro-1-methylcyclohexane with tert-BuO'/tert-BuOH is preferable over 2-Fluoro-1-methylcyclohexane when forming a cyclohexyl-methene (I think this is right nomenclature: cyclohexane with a methyl group double bonded to it)? I thought that since primary and tertiary alkyl halides react as E2 with strong bulky bases, it can be either 1-Fluoro or 2-Fluoro... This is from Item 141 AAMC test 10.