I'm currently finishing my amb care rotation at an outpatient cardiology clinic (awesome rotation) and have dealt with the old and new cholesterol guidelines, as well as JNC-7 and JNC-8. You could always do a presentation on the differences between either set of guidelines. The new cholesterol guidelines are interesting as the treatment recommendations and goals of therapy are different from the previous guidelines.
You could also do something diabetes-related. The new drugs that increase renal excretion of glucose such as canagliflozin (Invokana) and dapaglifozin are gaining momentum in the ambulatory and retail pharmacy settings.
