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- May 30, 2015
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Which class of enzymes is primarily responsible for the release of free glycerol from stored triglycerides?
A) Carboxylases
B) Phosphorylases
C) Lipases
D) Hydrolases
Answer is C. Why isn't D the answer? Don't lipases use water to break the fatty ester linkage?
This was TPR's explanation: "Fatty acid lipases act at specific positions along the glycerol backbone of triglycerides to, in the case of pancreatic lipase, digest dietary triglycerides. Hormone sensitive lipase works similarly, mobilizing stored triglycerides by hydrolysis of the fatty acid-glycerol ester linkage in response to glucagon (choice C is correct). Carboxylases catalyze the decarboxylation of amino acids, β-keto acids and α-keto acids (choice A is wrong). Phosphorylases catalyze the addition of a phosphate group (choice B is wrong) and hydrolases cleave bonds by addition of water (choice D is wrong)."
A) Carboxylases
B) Phosphorylases
C) Lipases
D) Hydrolases
Answer is C. Why isn't D the answer? Don't lipases use water to break the fatty ester linkage?
This was TPR's explanation: "Fatty acid lipases act at specific positions along the glycerol backbone of triglycerides to, in the case of pancreatic lipase, digest dietary triglycerides. Hormone sensitive lipase works similarly, mobilizing stored triglycerides by hydrolysis of the fatty acid-glycerol ester linkage in response to glucagon (choice C is correct). Carboxylases catalyze the decarboxylation of amino acids, β-keto acids and α-keto acids (choice A is wrong). Phosphorylases catalyze the addition of a phosphate group (choice B is wrong) and hydrolases cleave bonds by addition of water (choice D is wrong)."