If you graduate from a neurosurgery residency, be it ACGME or AOA, you will be able to practice pretty much anywhere you want. You will have a tough time getting employment in an ACGME academic center if you graduate from an AOA program, and, as someone mentioned above, you will never be a chairman of an ACGME program as a DO, regardless of where you train.
I also wouldn't listen to SurgeDO (no offense). If you like neurosurgery, go for it. If you are hard working, personable and driven, you can make it.
I would modify the steps listed by SurgeDO:
1. Do well in school and on boards. This is a given
2. Do 3-4 away rotations and be the most hard working & dedicate med student they have ever seen. Show you have a great personality and get along well with everyone. Get three amazing letters out of your aways. Become a known commodity.
3. Get some research out if you can but don't compromise #1&2.
4. Be lucky. Even the best students run into bad luck and any DO matching neurosurgery (either AOA or ACGME) will need a little luck.