Carbamazepine Overdose

[maldini99]

in carbamazepine overdose does enterohepatic recirculation affect the drug levels?
for instance would the level trend downward for a few draws and then go up again?

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[Daiphon]

in carbamazepine overdose does enterohepatic recirculation affect the drug levels?
for instance would the level trend downward for a few draws and then go up again?

Potentially; thus why we use multiple-dose charcoal to interrupt said enterohepatic circulation. Gotta love turning the gut lumen into an en vivo dialysis membrane. d=)

-t

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[BADMD]

CBZ can also have very erratic absorption in overdose. Levels can look stable for a few draws and then spike.