I've used it in both the OR and ICU setting. Has the potential to be useful, but I find it VERY POSITIONAL especially in the sedated moving ICU patient or in OR cases where you don't have access to the head for repositioning the device. In my experience, minimal movement you can cause you to lose your signal. To my knowledge, it is most validated in general/colorectal surgery for ERAS protocols assessing cardiac output and fluid responsiveness to limit fluid administration. The bottom line is it is a first generation of a technology that no doubt will be improved to become more user friendly.