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- Dec 19, 2013
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Ben and Jill who are both 30 years old want to have a baby.
Jill’s sister has a child affected with cystic fibrosis.
What is the risk that Jill is a carrier for the disease allele?
The answer given is 50%.
I understand CF is a AR disease. However how do we figure out Jill's parent's genotype to draw a punnet square and figure out her chance of being a carrier. (All we really know is her sister has an affected child so most likely her sister is a carrier... from this how do we extrapolate?)
Jill’s sister has a child affected with cystic fibrosis.
What is the risk that Jill is a carrier for the disease allele?
The answer given is 50%.
I understand CF is a AR disease. However how do we figure out Jill's parent's genotype to draw a punnet square and figure out her chance of being a carrier. (All we really know is her sister has an affected child so most likely her sister is a carrier... from this how do we extrapolate?)