Glucose reabsorption and osmotic diuresis

[MudPhud20XX]

Inhibition of proximal tubule reabsorption of glucose will tend to cause what change in renal function?

A. Decreased renal blood flow
B. Excretion of protein
C. Increased GFR
D. Metabolic acidosis
E. Osmotic diuresis

Answer: E

The solution says that all glucose should be reabsorbed by the proximal tubule. Inhibition of glucose transport leaves extra solute in the tubular fluid. The osmotic effect of this increases urine flow, an osmotic diuresis.

--> Can anyone explain why more glucose in urine will lead to increased urine flow??? Is it just simply b/c glucose increases urine osmolarity, it sucks up all the fluid into the lumen of the tubule thus making more urine?

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[swoopyswoop]

same reason Na+ in the lumen increases urine. they both osmotically draw water out with them.