A 2-year-old boy with normal size, weight, and development is brought to the physician because of a painful, swollen left knee for the past week. He has had two episodes of asymptomatic hematuria during the past 6 months. Both parents are healthy. He has achieved developmental milestones at appropriate ages. His height and weight are at the 70th percentile. Examination shows bruises and resolving hematomas on both elbows and signs of cutaneous hemorrhages at the site of a deep splinter. Laboratory studies show:
Hemoglobin 12 g/dL
Erythrocyte count normal
Leukocyte count normal
Bleeding time normal
Partial thromboplastin time increased
The most likely diagnosis can be proven by the therapeutic response to a single injection of which of the following materials?
A. Factor I (fibrinogen)
B. Factor VIII (antihemophilic factor)
C. Factor IX (plasma thromboplastin component)
D. Folic acid
E. Vitamin K
What is the dx ?
Hemoglobin 12 g/dL
Erythrocyte count normal
Leukocyte count normal
Bleeding time normal
Partial thromboplastin time increased
The most likely diagnosis can be proven by the therapeutic response to a single injection of which of the following materials?
A. Factor I (fibrinogen)
B. Factor VIII (antihemophilic factor)
C. Factor IX (plasma thromboplastin component)
D. Folic acid
E. Vitamin K
What is the dx ?