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I've never heard of a school holding that against someone. As long as you have enough science classes for them to judge your aptitude, it shouldn't make a difference.Do schools ever hold it against students if they are taking prereqs during the application process? For example, if I haven't taken orgo II yet (I couldn't take it this year because it conflicted with something I needed to graduate on time, and it's only offered once per year) but I already took the MCAT and I will take orgo II while applying next fall, will that ruin my chances anywhere?