Overall, it's spontaneous. But each step can be either spontaneous or non-spontaneous. For non-spontaneous ones, they are usually coupled with spontaneous ones. (e.g. ATP hydrolysis)
As @Zoey_imbmida said, some specific reactions within respiration can be spontaneous or non-spontanteous (think about the energy required to start glycolysis versus the products after the last step of glycolysis), but overall the process is spontaneous. If it weren't and we ended with a net loss of energy then it clearly wouldn't be a very good energy-enriching system to have.
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