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I think we dont know jack about how to stop a fibroblastic response, no antifibrosis agent works (if fibrosis is a single entity or a common presentation of multiple underlying pathways is another thing). From keloids to ipf nothings works real good, or at all. Get that and the nobel is within your reach.
Some of the guys at my shop have evidence for an antifibrotic agent. Just got a large large grant to look at it much closer.
Lung fibrosis of the type seen in IPF has much in common with metastatic cancer.