Propranolol ER vs propranolol SA

Discussion in 'Pharmacy' started by ronkoshy, 01.10.11.

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  1. ronkoshy

    ronkoshy 2+ Year Member

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    Last edited: 08.23.14
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  3. PharmD RPh

    PharmD RPh 2+ Year Member

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    1st of all how was the RX written? Propranolol ER, XL etc.? If so, sub what you want. Judging from what I could tell from the orange book website, it appears Innopran XL has a BX rating meaning that there is insufficient evidence to rate propranolol xl as a generic equivalent. Disclaimer: I'm not orange book expert and find it to be a very confusing reference. I'm guessing your computer just has two different manufacturers that are the same listed differently?
     
  4. All4MyDaughter

    All4MyDaughter SDN Mommystrator Staff Member Lifetime Donor SDN Administrator 10+ Year Member

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    I don't get the same thing when I look at Lexi. I see that all the capsules are 24 hour preparations and all the tablets are immediate release. The Orange Book backs this up. Sounds like if the doctor wrote for InnoPran you have to use THAT specific product b/c of the BX rating. But if they just wrote for once daily propranolol (pick your strength) you should be good to use whatever capsule you have on hand. But you could check the orange book if you were uncertain about specific manufacturers.
     
  5. ronkoshy

    ronkoshy 2+ Year Member

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  6. PharmD RPh

    PharmD RPh 2+ Year Member

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    Correct me if I'm wrong but Innopran doesn't come in a 60mg strength? In that case, I sub whatever generic propranolol Xl/ER 60mg cap I have.
     
  7. ronkoshy

    ronkoshy 2+ Year Member

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    Last edited: 08.23.14
  8. J ROD

    J ROD Watch my TAN walk!! Lifetime Donor 10+ Year Member

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    I would use them as the same.....
     
  9. Philboyds

    Philboyds

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    Does anyone see a problem with this (and many other) threads?
    Noone actually answered the question, then it wandered off in whatever direction the first response took it in. (The guy who didn't know but someone told him they are the same so he just started using them interchangeably.)
    Does anyone actually know the difference? What do the SA, ER, etc etc stand for? Why were they designated as different in the first place (even if may be now they are truly not different)
    I Am just complaining about the lack of scientific thinking and actual knowledge and verification that one would expect from people in a complex scientific field such as MEDICINE!!!

    Unbelievable.
     
  10. rxlea

    rxlea Almost a unicorn Moderator Emeritus 5+ Year Member

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    Extended release and sustained action. They are the same, just made by different companies... Now, if one was a tablet and the other was a capsule, they would be different.

    In ths case they are the same and interchangeable.
     
  11. cycloketocaine

    cycloketocaine 7+ Year Member

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    Lol...your first post is bitching about how off topic we go?

    Awesome.
     
  12. KARM12

    KARM12 Super Member 10+ Year Member

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    And resurecting an almost 2 yr old thread to bitch about it!
     
  13. bacillus1

    bacillus1 7+ Year Member

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    Where I work, SA is how the long-acting form of pretty much every drug on our formulary shows up in our system (morphine SA, metoprolol SA, etc...).
     

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