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Why are most abdominal aortic aneurysms located below the level of renal arteries?
The most common cause of abdominal aortic aneurysm is atherosclerosis.Atherosclerosis preferentially affects the abdominal aorta.Why are most abdominal aortic aneurysms located below the level of renal arteries?
The most common cause of abdominal aortic aneurysm is atherosclerosis.Atherosclerosis preferentially affects the abdominal aorta.
The aorta itself is supplied by small blood vessels called the vasa vasorum.
You've gotta know that the vasa vasorum ends at the level of the renal arteries.
This means the abdominal aorta below L2 is dependent on luminal O2 diffusion for adequate oxygenation.
In turn, this means the aorta is thinner below L2, thereby predisposing to aneurysm.
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Now that I answered yours, maybe you'll respond to my thread on interferon?
Endothelial cell injury is the first step in that process. Without vasa vasorum, the rate of vessel repair is lesser.
is the concept of no vasa vasorum below the renal arteries from goljan lectures?
I only listened to about half of the lectures so I'm not really sure. I don't even know where I had learned/heard that from.
is the concept of no vasa vasorum below the renal arteries from goljan lectures?
according to Robbins, the medial weakening in AAA is due to increased diffusion distance to the INNER part of the media due to atherosclerosis (versus a thoracic aortic aneurysm, which the outer part of the media is ischemic from the vaso vasorum being narrowed by hypertension)
since that part of the aorta is the most common place for atherosclerosis, that's why there is the medial weakening and aneurysm there