SDN Members don't see this ad. (About Ads) Hi. I was wondering if there where ever performed a surgery where someone had the part of the brain where a certain memory was located removed? If done, that would also mean that you would cut out surrounding memories or brain function. I have a particular memory that is ruining my life, and I would gladly sacrifice other brain function or memories for to have it removed. Preferably I would love to see Todd Sacktor's experiment with PKM Zeta inhibition in rats performed on humans (one of his studies: http://www.downstate.edu/pharmacology/faculty/sacktor.html). It effectively reset the surrounding neurons where the inhibitor was applied. Would any experimental surgeon with the patients consent be able to try this method? I'm considering gambling with ECT, but as far as I have learned, practitioners doesn't target specific memories with this practice. It's use isn't even meant to cause retrograde amnesia. If the PKMζ inhibition works on humans, the side effect would probably only mean that you had some set of neurons having a clean slate. ECT can cause brain damage, inner bleeding etc. Any insight? Thank you!