Response of bone to exogenous PTH in pseudohypoparathyroidism

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Electricity

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Pholston says that

exogenous PTH in pseudohypoparathyroidism [causes] normal effects at bone but expected non-response at the kidney​

But BRS Physio 5th ed says that pseudohypoparathyroidism

is the result of defective Gs protein in kidney and bone, which causes end-organ resistance to PTH.​

Which suggests that exogenous PTH should not have normal effects at bone. I tried to google search for about 5 mins and couldn't find any way to tell. Can anyone please clarify?

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Yeah, I'm not aware of there being a different PTH receptor at the bone than there is in your kidney, so you would expect that a mutation would knock-out function in both organs.

Pholston, are you aware of a finer point to this? It wouldn't surprise me if there was one -- for such an unassuming little glands, the parathyroids and PTH are quite complicated.
 
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