SSRIs without 2D6 metabolization

[birchswing]

Is there a chart somewhere that shows how each SSRI is metabolized? In particular, I'm curious if there is one that doesn't use Cytochrome P450 2D6.

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[nitemagi]

http://drug-interactions.com

 

[shan564]

Paroxetine and fluoxetine use 2D6 to a significant extent. Sertraline and (es)citalopram use little to none. The geriatric psychiatrists at my institution hate using fluoxetine or paroxetine for anything.

Here's the result of a quick google search:
http://www.preskorn.com/books/ssri_s6.html

 

[Shikima]

But if that's all you have to work with due to unique biochemistry..

 

[PikminOC]

Brintellix
has elderly indication