Menu Icon Search
Close Search

About the ads

  1. If you prefer the SDN Blue style, go to the bottom left of the page and select "SDN Blue"

What's the difference between DNA polymerase I and III

Discussion in 'DAT Discussions' started by ROCOCO8, 01.12.12.


  1. Thanks to Crack the DAT

    Thanks to DAT Destroyer
  1. ROCOCO8

    ROCOCO8

    Joined:
    08.12.11
    Messages:
    97
    SDN 2+ Year Member

    SDN Members don't see this ad. (About Ads)
    I'm a little confused about this..
    What's the difference bw I and III? .I always thought E. coli/bacteria only have DNA poly III...?
  2. Blue87Fiero

    Blue87Fiero

    Joined:
    09.21.10
    Messages:
    239
    Status:
    Dental Student
    SDN 2+ Year Member
    I don't know which ones E.Coli has for sure but I thought I, II, and III all came from E.Coli. I actually thought it went up to five. I think DNA III was the biggest DNA Pol I was unique because it could "proof read" in both directions 5' to 3' and 3' to 5'. I am not sure if I am right on this I might check tomorrow if I remember. I just finished genetics and I should know this.
  3. ROCOCO8

    ROCOCO8

    Joined:
    08.12.11
    Messages:
    97
    SDN 2+ Year Member
    Oh well that makes more sense... But which type of polym do humans use?
  4. Ferferi

    Ferferi

    Joined:
    08.29.11
    Messages:
    71
    Location:
    Santa Clarita, CA
    Status:
    Pre-Dental
    SDN 2+ Year Member
    I wasn't sure about the answer so I googled it and this is what I got

    DNA Polymerase III - makes the chain in a 5 to 3 direction and it proofreads with a 3 to 5 exonuclease, so it goes both ways doing something different
    DNA Polymerase I - breaks down the RNA primer with a 5 to 3 exonuclease.
  5. Dotoday

    Dotoday

    Joined:
    05.27.07
    Messages:
    1,546
    SDN 7+ Year Member
    The Molecular bio nomenclature states that DNA Polymerase I, II, and III is used in procaryotes like E-Coli. Eucaryotes use DNA Polymerase alpha, beta, delta, epsilon.

    DNA Polymerase III is responsible for leading and the lagging strand synthesis in bacteria. DNA Polymerase I replaces RNA primer with the DNA strand.

    Sent from my MB855 using Tapatalk

// Share //

Style: SDN Universal