About the ads

Why do steroids cause an increase in WBC?

Discussion in 'Allopathic' started by Digginit, Sep 16, 2003.

  1. SDN is a nonprofit organization. Services are made possible through the generous support of SDN members and sponsors. Thank you.
  1. Digginit

    Digginit Junior Member

    Joined:
    Oct 28, 2002
    Messages:
    22
    SDN 7+ Year Member

    SDN Members don't see this ad. (About Ads)
    What's the mechanism for it? Surely some really smart medical student knows.....

    Digginit!
  2. ckent

    ckent Removed

    Joined:
    Jul 31, 2000
    Messages:
    2,138
    Location:
    Smallville/Metropolis
    It causes white blood cells to be released from endothelial walls and go into the blood stream, allowing them to be counted in your CBC.
  3. dr barb

    dr barb Member

    Joined:
    Dec 17, 2002
    Messages:
    67
    Location:
    LA (NOT Louisiana)
    SDN 7+ Year Member
    Steroids increase the concentration of neutrophils in your blood (causing and increase in WBC's but without bandemia) by preventing their infiltration to the site of injury, and hence, directing them to the circulation instead of the injured tissue. These are mature neutrophils so you don't see an increase in bands (immature neutrophils).
  4. Talula

    Talula Junior Member

    Joined:
    May 27, 2003
    Messages:
    18
    SDN 7+ Year Member
    Yep, a phenomenon also known as "demargination." Gotta give it a name that the 'lay' public doesn't understand to make us feel super smart :rolleyes:
  5. phllystyl

    phllystyl n0t the j0ke f0rum!@RAWR@

    Joined:
    Mar 10, 2002
    Messages:
    1,869
    Location:
    Philly -> NYC -> Philly (in 2009)
    SDN 7+ Year Member
    ]


    I actually think demargination is a perfect descriptor of it, just as margination is perfect descriptor of the opposite.
  6. Digginit

    Digginit Junior Member

    Joined:
    Oct 28, 2002
    Messages:
    22
    SDN 7+ Year Member
    Great! Thanks!

Share This Page


About the ads