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Why never vicoprofen?

Discussion in 'Pharmacy' started by npage148, Dec 19, 2012.

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  1. npage148

    npage148 Senior Member

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    For real? More effective, no hepatic toxicity, more dosing flexibility (take 1 to 4 tabs safely). Did it just lose a marketing battle like lisinopril vs enalapril?
  2. bacillus1

    bacillus1

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    Well, narcs are already pretty GI-irritating. Adding an NSAID probably doesn't help the situation. But I agree that I would still imagine more of it being used more...probably a bit of a marketing thing.
  3. npage148

    npage148 Senior Member

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    I can see the gi thing but usually the patient also has a script for IBU or is told to take OTC IBU.
  4. bob1234

    bob1234

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    We see it infrequently. Most patients who have liver issues are written oxycodone or plain hydrocodone (which I do think is not even available anymore, but they keep writing for it!).
  5. BMBiology

    BMBiology on maternity leave (again)

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    Probably because IBU 200mg doesn't have much anti-inflammatory effect so people think it's not effective. Must take more tabs but that also mean more hydrocodone.

    I would make a tab with IBU 600mg
  6. pinipig523

    pinipig523 I like my job!

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    I give vicoprofen for kidney stones.
  7. atpsynthase

    atpsynthase Protons and Pumps, Baby!

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    Seems like a lot of older patients would benefit more from the APAP formulation since there is less GI irritation, is probably safer in patients with OA associated pain, less impact on GFR, and relatively speaking... Fewer interactions. The FDA limiting the APAP content to 325 mg or less will help with hepatotoxicity, too. Physicians like to go from APAP to tramadol it would seem, too... Or only try one NSAID rather than trying a few. So idk I'm sure it could have a place in therapy but I don't normally see Rx strength ibuprofen scripts with Vicodin/norco scripts either.
  8. Sparda29

    Sparda29 En Taro Adun Gold Donor

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    They should just eliminate the APAP and IBU formulation and sell it as pure hydrocodone.
  9. npage148

    npage148 Senior Member

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    But then it would be a c-II
  10. aznkukuboi

    aznkukuboi

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    I dispense vicoprofen for one of my pts on workers comp. Not many docs even knows it exists.
  11. rph3664

    rph3664

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    I remember one customer who was on it long-term, but most of the RXs I've seen were from dentists.
  12. Ackj

    Ackj

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    It happens anyway in NY on February 23.
  13. VA Hopeful Dr

    VA Hopeful Dr Senior Member

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    Isn't it still brand name only?
  14. Old Timer

    Old Timer SDN Advisor SDN Advisor

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    First:

    There are no formulations of "Pure" Hydrocodone. You can get the Hycodan generic which contains subtherpeutic amounts of an antimuscarinic to prevent IV abuse. It's really the reason there is APAP in formulations.

    Secondly, to answer the OP, it's because the amount of Ibuprofen is too low to be meaningful. Remember, the OTC dose is 400mg. So what good does the 200mg do? They should either make it 7.5/400 or 5/200.
  15. bacillus1

    bacillus1

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    Well, Percocet is 5/325, also with a low dose of APAP. 325mg of APAP really isn't very effective either.
  16. rph3664

    rph3664

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    Whatever happened to Zohydro (I think that's what it was going to be called)?
  17. Old Timer

    Old Timer SDN Advisor SDN Advisor

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    I agree, the APAP is worthless unless you double up to two tablets except for the fact that the APAP keeps you from injecting it IV.
  18. pinipig523

    pinipig523 I like my job!

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    Apap is there to prevent you from overdosing on it and to limit the number of doses per day.
  19. Farmercyst

    Farmercyst Lowest common denominator Moderator Emeritus

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    OTC dose is 200. :confused:

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  20. croquemonsieur

    croquemonsieur

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    Maybe you're confusing dose with strength?
  21. zelman

    zelman

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    Why never combunox?
  22. npage148

    npage148 Senior Member

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    Now that it's generic I agree!

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