dobutamine for cardiac stress testing

[MudPhud20XX]

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FC explaines the reason dobutamine is used for cardiac stress testing is

• Dobutamine is used in cardiac stress testing as it increases cardiac output without causing vasodilation and reflex tachycardia due to concurrent β2-receptor activation.

But if there is concurrent b2 activaiton won't that lead to vasodilation? Why is it saying the opposite?

 

[Jabbed]

Dobutamine is functionally beta1 selective

 

[Instatewaiter]

FC explaines the reason dobutamine is used for cardiac stress testing is

• Dobutamine is used in cardiac stress testing as it increases cardiac output without causing vasodilation and reflex tachycardia due to concurrent β2-receptor activation.

But if there is concurrent b2 activaiton won't that lead to vasodilation? Why is it saying the opposite?

First, the vasodilation is mainly peripheral.

Second, it is used mainly because it increases myocardial oxygen demand by increasing heart rate, stroke volume and contractility. These dwarf the vasodilation, thus you get wall motion abnormalities in ischemic territories.