renal; pharmacology

  1. S

    Bicarbonate diuresis

    Hi, in Katzung's it says this of the effect of acetazolamide: "The major renal effect is bicarbonate diuresis (ie, sodium bicarbonate is excreted); body bicarbonate is depleted, and metabolic acidosis results. As increased sodium is presented to the cortical collecting tubule, some of the...