After a little over a year out, I am happy to take few questions as a practicing clinician scientist (MD PhD w VA Merit/NIH funding and clinical neurologist). For applicants: read the FAQs, they have a lot of useful and accurate information. High MCATs/GPA increase your likelihood to get in, but even for a MCAT of 40, there is a 3-8% chance of not getting in. Why? Poor amount of clinical shadowing, not sufficient commitment to research, something bad on your application (i.e.: DWI, etc.), terrible interview, poor GPA, etc. Clearly, if you repeat these odds across many programs, you get in somewhere. For MD PhD students: enjoy the ride; these are great years. Although you will not make as much as your exclusively clinical colleagues (~ 30-40% less), you will do well economically (better than ok), and retire with few $ M (if you live within your means, contributing to your university's 401K). The most important thing is that you will get to do what you love, get paid for it, and leave a great "footprint" in Medicine and Science.