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Discussion in 'MCAT Discussions' started by Demihorvat, Aug 21, 2015.

  1. Demihorvat

    2+ Year Member

    Oct 1, 2013
    Likes Received:
    Medical Student (Accepted)

    I was wondering for phosphopantothenate in aq. solution of ph = 7, how come both the OH's on the phosphate group are deprotonated. I googled the pKa's of the OH groups on the phosphate, and it tells me that pka1 is around 2 while pka2 is around 7. So why does the 2nd OH deprotonate in this case? If we didn't know the pka's, how do we know that both the OH's will be deprotonated?
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