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Discussion in 'NBDE Exams & Licensure Exams' started by incisorgirl, May 1, 2007.
procollagen is formed at which level
decks says ER and in kaplan its GOLGI
is formed at ER level esp. RER
ans is golgi.
Three peptide chains are formed (2 alpha-1 and 1 alpha-2 chain) in ribosomes along the Rough Endoplasmic Reticulum (RER). These peptide chains (known as preprocollagen) have registration peptides on each end; and a signal peptide is also attached to each
Peptide chains are sent into the lumen of the RER
Signal Peptides are cleaved inside the RER and the chains are now known as procollagen
Hydroxylation of lysine and proline amino acids occurs inside the lumen. This process is dependent on Ascorbic Acid (Vitamin C) as a cofactor
Glycosylation of specific hydroxylated amino acid occurs
Triple helical structure is formed inside the RER
Procollagen is shipped to the golgi apparatus, where it is packaged and secreted by exocytosis
thank u so much
one more question
in salivary glands,secretory granules are exocytosed from the apical cytoplasm,under
Salivation is parasympathetically mediated.
in salivary glands
lining of intercalated duct--simple cuboidal or simple columnar
and of excretory duct is-stratified columnar or stratified squamous
apical cytoplasm of secretory end piece(in sal. glands) has abundant
in cell membranes,location of choline and amine containig phospholipids ?
in cell membranes,location of choline and amine containig phospholipids ?[/quote]
choline containig phospholipids are enriched in outer leaflet of the lipid bilayer
amine containig phospholipids are found mainly in inner leaflet