Anyone have a good mnemonic for 1st and 2nd gen antihistamines?

CityDweller

Junior Member
10+ Year Member
Jun 29, 2006
30
0
Status
Resident [Any Field]
this is not much but i hope it helps. the 2nd generation that are less sedating:

Desloratadine, loratadine, fexofenadine, cetirizine

Don't Let u Fall aSleep
 

myry

countdown
7+ Year Member
15+ Year Member
Jul 18, 2003
57
2
Visit site
Status
this works for me:

you must first chant "dimen, diphen, chlorphen" before you fall asleep.

so first gen. is dimenhydrinate, diphenhydramine, chlorpheniramine...and these are more sedating
 
About the Ads
Nov 19, 2009
2
0
Status
Pre-Medical
2nd generation: nonsedating, keep you A-wake, end in A-dine (must stay awake to dine)
- DesloratADINE
- FexofenADINE
- LoratADINE

Also, cold air helps to stay awake, so "CET (set) the AC to stay awake"
- CETirizine
- ACivastine

Be careful with the H2 blockers which end in -IDINE
 

bassvp

MS4--Doing the derm dance...
7+ Year Member
Apr 13, 2010
529
6
Status
Medical Student
Not that you have much time to watch TV, but it's helpful to remember that anything marketed currently is 2nd generation and non-sedating:

Claritin (loratadine)/Clarinex (desloratadine), Zyrtec (cetirizine), Allegra (fexofenadine)
 

mdquestion

5+ Year Member
Jul 6, 2009
157
0
Status
I'd just try and memorize the 1st gen. And just remember that the second gen are non-sedating and usually end in -adine.

The only time I've really seen this come up on an exam (1) switching a patient from a 1st generation to a 2nd generation because of drowsiness (2) avoiding using 1st generation drugs with benzo's because they can have additive sedative effects.
 
About the Ads