At the predent level this isn't really something to worry much about, but I get the curiosity, I was the same way. The most important thing you can do right now is to go to the cheapest school possible - this will give you freedom to have more liquid cash on a month to month basis because of the lower monthly student loan payment. Banks care about how much cash comes in and how much goes out per month, how much collateral you have, your credit score, and your business plan. Big student debt will not necessarily prohibit you from getting a practice loan, but it will force you into a higher monthly repayment, equating to less free cash per month, which hurts your overall loan application. Dentists are the 2nd least risky borrowers, second only to funeral homes, and banks know this. That said, times are changing, schools are proliferating, tuition is increasing dramatically every year, and purchasing a practice may not always be as safe of an investment.