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u mean no intermittent jaundice, farmer? why in books it stated that?
for manna, I'm not asking bout causes of jaundice, but more on INTERMITTENT jaundice. anyway thnx for ur reply
With primary sclerosing choangitis, an autoimmune phenomenon, there is "intermittent" jaundice which correspond to episodes of autoimmune attacks of the posthepatic (and sometimes intrahepatic) biliary tree, leading to acute obstruction. These attacks are what eventually lead to the "beading" seen on ERCP (endoscopic retrograde cholangiopancreatography). Repeated inflammatory episodes can consequently lead to chronic post or intra-hepatic biliary obstruction as a result of inflammation and fibrosis of the bile duct or biliary tree.