Lifetime Donor
7+ Year Member
Jan 17, 2012
Osaka, Japan
what's the impact of thymic aplasia on humoral immunity?
There's an NBME question on this, and they want you to know humoral/B cell function is completely normal in DiGeorge. In theory, yes, T cells activate B cells, but any B cell-related insufficiency that carries over humorally is significantly lesser compared to SCID, for instance.