If you are changing what classes you will be taking, I would let them know, since it will help them verifiy your transcripts. How you go about doing that, good question!
I called NYU since that was the only secondary I turned in that asked when I was taking my second english class and I changed that to meet with cornell's rule of having it done before january. He said just to write a letter to them and that they ask for another transcript at the end of this semester anyway so it wasnt that big of a deal. Hope this helps...
on amcas is says current and future coursework is nonbinding, but should be provided to give medical schools an idea of what you plan to take during the coming year.
as long as your application has been processed and verified, change away.
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