I think some of the people here might be overestimating the impact that this incident might have. Indeed, I think the applicant has a tough road ahead, but I don't think med school is out of the question. What you have to realize is that many people posting here are those who are right now applying, not those who have already gone through the process and are in med school. I happen to know people with red flags on their record (including cheaters, and even a felon, though she was 13 when convicted...) who are now in med school. Med school admissions members are tough, but they are usually also quite understanding and forgiving. I think that when used correctly, these characteristics are what make many of them such outstanding doctors. So your friend should do everything in his power to correct his mistake. In my mind, nothing he has done is irreversible for the sake of his future (though others will disagree). The only way your friend can be sure that he doesn't get into med school is if he doesn't try...but he will need to try very hard. In short, don't let him give up, and help him as much as you can.