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10+ Year Member
Nov 22, 2008
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  1. Pre-Medical
Which class of drugs acting on the autonomic nervous system would be expected to cause difficulty urinating?
And which class of drugs would exacerbate a patients suffering Shy-Drager syndrome symptoms?


Full Member
10+ Year Member
Nov 24, 2007
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  1. Medical Student
I hope I'm not doing your homework for you... but:

urination is under both parasympathetic and sympathetic control. So drugs that inhibit the action of autonomic receptors (alpha-adrenergic, beta-adrenergic, nicotinic, muscarinic) could both cause difficulty urinating (although I think this would be a severe side effect) and exacerbate the symptoms of someone with Shy-Drager disease.

do a search of drugs that are alpha-adrenergic antagonists, beta-adrenergic antagonists, etc and you'll find some specific examples.


10+ Year Member
Sep 29, 2007
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  1. Attending Physician
Anticholinergics and alpha agonists should both cause decreased urge/ability to void.
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