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Clinical query

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cookiedr

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Which class of drugs acting on the autonomic nervous system would be expected to cause difficulty urinating?
And which class of drugs would exacerbate a patients suffering Shy-Drager syndrome symptoms?
 

coldweatherblue

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I hope I'm not doing your homework for you... but:

urination is under both parasympathetic and sympathetic control. So drugs that inhibit the action of autonomic receptors (alpha-adrenergic, beta-adrenergic, nicotinic, muscarinic) could both cause difficulty urinating (although I think this would be a severe side effect) and exacerbate the symptoms of someone with Shy-Drager disease.

do a search of drugs that are alpha-adrenergic antagonists, beta-adrenergic antagonists, etc and you'll find some specific examples.
 

cpants

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Anticholinergics and alpha agonists should both cause decreased urge/ability to void.
 
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