coronary artery disease and valve disorder

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trgf

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What would be the connection between coronary artery disease and valvular disorders? I know that the valves do not have any blood supply, and as such trying to increase neutrophils would be useless in treating bacterial endocarditis.But so, wouldn't the same line of reasoning apply here?

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The basic mechanism underlying coronary disease is ischemia, so we must think how this can damage valvular function. Valves are "operated" by papilary muscles without these they won't open or close. So, if you have infarction of an artery supplying a papillary muscle the valve stops normal function and you probably will have regurgitation.
 
The basic mechanism underlying coronary disease is ischemia, so we must think how this can damage valvular function. Valves are "operated" by papilary muscles without these they won't open or close. So, if you have infarction of an artery supplying a papillary muscle the valve stops normal function and you probably will have regurgitation.

1. Aortic and Pulmonic valves aren't associated with papillary muscles.

2. Papillary muscles don't open and close valves. They prevent the valves from ballooning into the atria (prevent regurge)

I do agree with the part about ischemia--->necrosis--->regurge at the AV valves.

Perhaps with the Aortic valve, assuming the person has atherosclerosis elsewhere, that would lead to increased afterload and increased pressure of blood flowing across the valve. Maybe that will lead to faster wear and tear, leading to stenosis quicker?

I'm not sure.
 
The basic mechanism underlying coronary disease is ischemia, so we must think how this can damage valvular function. Valves are "operated" by papilary muscles without these they won't open or close. So, if you have infarction of an artery supplying a papillary muscle the valve stops normal function and you probably will have regurgitation.

This :thumbup:

Patient comes to you post-MI with hypotension and dyspnea; you hear crackles in the lung and a pansystolic or midsystolic murmur at the apex. Probably an ischemic sequelae of the MI where the papillary muscle ruptured, causing mitral regurgitation.
 
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