I am guessing you are undecided between Creighton and UF?
I would go where you think you would be happiest, regardless of the money. If you are miserable, but saving money, does it really make it worth it (not saying that you would be miserable at UF)? What area of the country do you ultimately want to end up in? If you like the heat and want to end up in Florida, maybe UF would be the best bet. If you actually like the cold winter Omaha would be good. I moved somewhere completely different than where I am from for undergrad and loved it while I was there and it was a nice change.
Omaha may not be New York, Chicago, or LA, but who's to say that's a bad thing? I personally would never want to live in a huge city. Less temptations and distractions for one thing. Ultimately we are going to be broke dental students who probably couldn't afford to do any of the more luxurious, extravagant things that you can in New York, Chicago, or LA. A grey goose and Red Bull in New York will taste the same as a grey goose and Red Bull in Omaha, just probably at a much cheaper price. Who's to say you can't have as much fun out with friends in Omaha as in huge city? Sorry for the rant, I'm just a small town girl and Omaha is a big city in my eyes and has way more to offer than where I am currently located, and I don't need one of those major cities to be happy. (I've never been to Gainesville, but you could probably use the same argument for it vs. a major city)
In the long run you need to be ok with your decision. I know most people on here say go to the cheapest place and they make really good points about why, and I myself am going to my cheapest option and first choice school. However if the same school would have been the most expensive I still think I would have chose to go there because I believe I will be happiest there. I don't think you can put a price on happiness.
If at all possible maybe make a last minute visit to each place again before you make your final decision if you think that might help. Go to Gainsville check it out then go to Omaha. If you decide on Creighton while in Omaha, use it as a trip to find somewhere to live.