Does anyone know the basics of the mechanism for CF?
I know that with CF, you have a mutation in the CFTR channel, i.e. the one that is responsible for secretion of Cl in glands. Thus you don't secrete Na either, no water goes into the lumen and secretions are viscous. But I really don't see why would your sweat be "salty," i.e. high in NaCl. Aren't sweat glands just another type of exocrine glands? Am I missing something (well, obviously I must be...). Thanks in advance for any help.
I know that with CF, you have a mutation in the CFTR channel, i.e. the one that is responsible for secretion of Cl in glands. Thus you don't secrete Na either, no water goes into the lumen and secretions are viscous. But I really don't see why would your sweat be "salty," i.e. high in NaCl. Aren't sweat glands just another type of exocrine glands? Am I missing something (well, obviously I must be...). Thanks in advance for any help.