I'm not sure how many schools still use animals, but WAY back when, we did use animals, not for research, more for demonstration of effects of drugs on them. Actually it was pretty gruesome sometimes. We used rats and would put little pads over their eyes and shock them, then give them a dose of dilantin (through their tail) and shock them again to demonstrate the effects of the drug on the "seizure" we were inducing. We'd sedate them, stimulate them, and yes in the end euthanize them. Get caught hurting them intentionally, automatic F for the lab. One of the little critters bit me once, and I can't say I blame him. Bottom line, for me anyway, the lab was one of the most memorable and educational parts of my pharmacy education, and you won't find a bigger animal lover than me, and I'm not sure I could have done anything like this to a domestic animal but I don't recall being too traumatized using the rats.