Do Rh+ RBCs make anti-Rh- antibodies?

[Osakhomen]

So I know Rh- RBC can make Anti-Rh+ antibodies, but do Rh+ RBCs make anti-Rh- antibodies? My guess is no, because Rh- doesn't have the Rh antigen... but I'm not sure.

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[Thirteeen]

So I know Rh- RBC can make Anti-Rh+ antibodies, but do Rh+ RBCs make anti-Rh- antibodies? My guess is no, because Rh- doesn't have the Rh antigen... but I'm not sure.

Rh negative = absence of Rh factor

 

[PiBond]

So I know Rh- RBC can make Anti-Rh+ antibodies, but do Rh+ RBCs make anti-Rh- antibodies? My guess is no, because Rh- doesn't have the Rh antigen... but I'm not sure.

RBCs aren't the ones making antibodies either

 

[Osakhomen]

RBCs aren't the ones making antibodies either

okay I worded it wrong, b-cells/plasma cells are making the anti-bodies...

 

[GreenRabbit]

Remember that antibodies are supposed to target foreign antigens. Someone who is Rh- will produce antibodies against the Rh antigen because it doesn't exist naturally in their body. Someone who is Rh+ on the other hand will not produce antibodies against Rh because it is a product of their own cells.

 

[Osakhomen]

Remember that antibodies are supposed to target foreign antigens. Someone who is Rh- will produce antibodies against the Rh antigen because it doesn't exist naturally in their body. Someone who is Rh+ on the other hand will not produce antibodies against Rh because it is a product of their own cells.

thanks!