does a bulkier group or heavier group go on the equatorial position in a chair confirmation ?

D

dentalstudent2021

some places say it's the heavier group ? I always thought it was the more bulkier group.
 

Graffix

2+ Year Member
May 12, 2015
140
87
Status
Pre-Dental
Bulk - they prefer to be equatorial is to avoid interacting with other substituents and the ring if im not mistaken.
 

orgoman22

DAT DESTROYER
Lifetime Donor
Sponsor
Vendor
15+ Year Member
Mar 12, 2005
4,345
3,121
New York City
www.orgoman.com
Status
Non-Student
some places say it's the heavier group ? I always thought it was the more bulkier group.
Heavier means little......BULKIER is the more important factor. For example, a methyl group weighs less than a heavy bromine atom BUT takes up more volume of space, consequently the methyl group preferentially is placed equatorially. Hope this helps.



Dr. Jim Romano
 
About the Ads