Well, I frequently drive from the South Loop and there's usually no trouble getting to classes in the morning. The only trouble I've experienced is the commute back home. It usually gets bad around 2:00 pm - 7:00 pm, so you may want to avoid those hours because it'll take you about 50 minutes to get home. I would consider studying on campus until 8:00 pm or be a rebel by leaving early or stay home. During your first year, it may be hard to skip classes because you need to be anatomy for most of the day, so I suggest studying on campus if you feel like you want to stay around the South Loop area. During your second year, your schedule will be nicer and the commute won't be as bad.
Hope this helps,
Ms. Toast