- Jan 16, 2014
From what I understand when hemoglobin has increased affinity for oxygen the curve shifts left. When it has reduced affinity for oxygen it shifts right. Carboxyhemoglobin reduces the affinity of Hemoglobin for oxygen, so the curve should move right and yet in First Aid it says that Carboxyhemoglobin cause the curve to shift left and reduces the amount of oxygen unloaded into the tissues. What's going on here?